Lovd Scripts

Reading Frame Checker

The Reading Frame Checker allows you to to quickly generate a prediction of the effect of whole-exon deletions and duplications on the RNA translation. Amongst others, the script will check if the given deletion or duplication is in-frame or out-of-frame. It will also generate the HGVS name of the given mutation.

The Reading Frame Checker is only available for your gene database if you have once run the Reference Sequence Parser, because the Checker needs to know exon and intron information from your gene that the Reference Sequence Parser takes out of the GenBank file. Once available, it is also linked to from the gene homepage, in the "Graphical displays and utilities" table.

This feature was added in LOVD 2.0-22, released 2009-10-05.

« GenBank File Uploader

Reference Sequence Parser »